Isolation of a new soluble antigen from the yeast phase of Histoplasma capsulatum.
نویسندگان
چکیده
A method is described by which a soluble antigen was prepared from the yeast phase of Histoplasma capsulatum. This soluble preparation had a specificity greater than that of whole-cell yeast-phase antigens. In complement fixation tests with sera from human cases of histoplasmosis, blastomycosis, and coccidioidomycosis, the soluble antigen reacted in 12.1% of 141 tests with heterologous sera, whereas conventional whole-cell yeast antigens reacted in 47.3% of 91 tests with heterologous sera. The reactivities of the two types of antigens with homologous sera were essentially the same.
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ورودعنوان ژورنال:
- Applied microbiology
دوره 24 5 شماره
صفحات -
تاریخ انتشار 1972